3D Structure Determination of the Crh Protein from Highly Ambiguous Solid-State NMR Restraints
نویسندگان
چکیده
منابع مشابه
3D structure determination of the Crh protein from highly ambiguous solid-state NMR restraints.
In a wide variety of proteins, insolubility presents a challenge to structural biology, as X-ray crystallography and liquid-state NMR are unsuitable. Indeed, no general approach is available as of today for studying the three-dimensional structures of membrane proteins and protein fibrils. We here demonstrate, at the example of the microcrystalline model protein Crh, how high-resolution 3D stru...
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ژورنال
عنوان ژورنال: Journal of the American Chemical Society
سال: 2008
ISSN: 0002-7863,1520-5126
DOI: 10.1021/ja078014t